Azetidine-3-carboxylic methyl ester hrdrochloride - Names and Identifiers
Azetidine-3-carboxylic methyl ester hrdrochloride - Physico-chemical Properties
Molecular Formula | C5H10ClNO2
|
Molar Mass | 151.59 |
Melting Point | 93.0 to 97.0 °C |
Boling Point | 187-192℃ |
Flash Point | 69°(156°F) |
Water Solubility | Soluble in water |
Appearance | Crystalline powder |
Color | White to Almost white |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
MDL | MFCD01861758 |
Azetidine-3-carboxylic methyl ester hrdrochloride - Risk and Safety
Risk Codes | 36 - Irritating to the eyes
|
Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
|
Hazard Class | IRRITANT |
Azetidine-3-carboxylic methyl ester hrdrochloride - Introduction
Methyl azetidine-3-carboxylate hydrochloride is an organic compound with the chemical formula C5H9NO2 · HCl. Its nature is as follows:
1. appearance: colorless or light yellow solid.
2. solubility: soluble in water and organic solvents, such as alcohol and ether.
3. melting point: about 140-150 ℃.
4. stability: stable to light and heat.
Azetidin-3-carboxylic acid methyl ester hydrochloride has many applications in the chemical and pharmaceutical industries:
1. as a pharmaceutical intermediate: can be used to synthesize a variety of drugs, such as anti-rheumatic drugs.
2. catalyst: can be used as a catalyst for organic synthesis reaction, such as esterification reaction and etherification reaction.
3. preservatives: can be used for the preparation of preservatives and antibacterial agents.
Preparation of azetidine-3-carboxylic acid methyl ester hydrochloride:
The compound can be obtained by reacting methyl p-azetidine-3-carboxylate with hydrochloric acid. The specific procedure is to react methyl azetidine-3-carboxylate with excess hydrochloric acid under appropriate temperature conditions, followed by crystallization concentration or vacuum distillation to obtain the target product.
About its safety information:
1. azetidine -3-methyl formate hydrochloride on the eyes and skin irritation, should be washed with plenty of water immediately after contact.
2. avoid inhalation of its dust or vapor, should be used in a well-ventilated place.
3. Use should wear appropriate work gloves and safety glasses.
4. storage should be sealed, and away from fire and high temperature.
5. Please keep it properly and keep it away from children. If you take it by mistake or accidentally touch it, please seek medical attention immediately and take the packaging to the hospital.
Last Update:2024-04-09 21:54:55